From Downtown city center take I-690 East until exit 16S Thompson Rd South /635S/. Merge to the right just off the exit. Bear right on RT 5 Erie Boulevard. Hotel is on the right. The Hampton Inn - Suites Syracuse Erie Boulevard I-690 hotel is nestled just off major Interstate 690 with easy access to Interstates 90 - 81 as well. Our hotel is centrally located to meet the needs of any traveler. We are just moments from the Downtown Business District as well as Syracuse University - Lemoyne College. We are just a short drive from Carousel Center Mall NYS Fairgrounds museums and parks. Our hotel is built on the very sight of the old Erie Canal which was the main thoroughfare from Albany to Buffalo in the 1800*s and early 1900*s. This area of Syracuse is just a bustling today. Numerous restaurants shopping and entertainment for both adults - children are within walking distance of the hotel. The Syracuse area offers a lot of history as well. Take a trip to our Erie Canal Museum or Salt Museum and learn a little bit about Syracuse*s past. If scenery is more your thing then visit our Onondaga Lake Park Beaver Lake Nature Center or Green Lakes State Park. Our Hampton Inn hotel offers guests a delicious On the House Breakfast each morning. Our pool and fitness room are the perfect way to energize in the morning or to relax in the evening. Our Cloud 9 bed will ensure you have a restful nights* sleep. Our Perfect Mix Lobby is a wonderful place to relax and read the paper or meet with friends or colleagues. It is our goal to ensure you are 100 satisfied everyday and every stay. We love having you here at the Hampton Inn - Suites Syracuse Erie Boulevard I-690 hotel in New York. Parking