From I-85 North - Take Exit 78-221 Chesnee. Turn left and our hotel in Spartanburg SC is one block on the left. From I-85 South - Take Exit 78-221 Chesnee. Turn right and our hotel in Spartanburg SC is one block on the left. To Carolina Panthers Training Camp - Turn right out of hotel onto 221 - follow 221 for approx. five miles and turn left onto N. Church St. and continue Panthers Training/Wofford College on the left. nature history and culture in harmony welcome to the Hampton Inn Spartanburg-North I-85. Step back in time to the colonial era or indulge in modern luxuries and recreation in Spartanburg. The Hampton Inn hotel in Spartanburg-North I-85 is situated to offer easy access of the Duncan business centers and is within five minutes of Wofford College. Explore the natural beauty of the area at Croft State Natural Area Hatcher Garden and Woodland Preserve or Lawson*s Fork Creekall are located within minutes of our hotel in Spartanburg. Also visit the Magnolia Street Train Depot or take a ride in the Foothills Nature Equestrian Center. Dig deeper into the rich history of the area at the Spartanburg Regional Museum and the Cowpens National Battlefield a historic Revolutionary War site. or tour Morgan Square a historic district that also offers a vibrant nightlife. Our hotel in Spartanburg gives you easy access to culture at the Carolina Foothills Artisan Center. Take a short drive into Greenville for more historic landmarks and world-class entertainment. Ask the team at our Spartanburg hotel for more tips on the area*s many attractions. services - amenities Even if you*re in Spartanburg to enjoy the great outdoors we want you to enjoy our great indoors as well. That*s why we offer a full range of services and amenities at our hotel to make your stay with us exceptional. Are you planning a meeting. Wedding. Family reunion. Little League game. Let us help you with our easy booking and rooming list management tools. Parking