Take I85 South to Greenville Take Exit 51 off I-85 onto I-385 I-385 North leads to Downtown Greenville Go straight through two traffic lights and Hyatt Regency Greenville is on the left. Hyatt Regency Greenville is located on our award-winning Main Street in the heart of downtown. Tree lined streets lead the way to over 100 restaurants, 100 shops, nightlife, parks, and museums. Close proximity with easy access to all business locations within Greenville. Changes to the dates of stay, number of guests per room or number of rooms confirmed will be subject to current pricing which may be different than previously confirmed rates. -Extra beds on request, use /SI- field $15USD per night effective for stays 16OCT09 and beyond -No rollaways allowed in two double bedded rooms -Maximum 4 adults per room -Max of 3 rooms under one name Artfully stylish, contemporary and urbane, Hyatt Regency Greenville is a luxury hotel ideally located on Main Street in downtown Greenville. Our award-winning hotel offers a refreshing blend of Southern hospitality and modern, urban convenience. Whether you are visiting for business or family vacation, our downtown Greenville, SC hotel on NOMA Square is a dynamic retreat where you can relax, dine, meet, and play. Hyatt Regency Greenville is an inviting destination where you can experience the citys rich heritage, from arts to outdoor adventures. Tee off on beautiful golf courses, catch a favorite concert at Bon Secours Wellness Arena, be an ultimate driver at the BMW Performance Driving, or walk to over 60 restaurants and shops in downtown Greenville. Escape from your schedule and discover lush parks and the majestic Blue Ridge Mountains just minutes away from one of the most refreshing Greenville hotels. Parking 6.00 USD Take I-85 North Take Exit 51 off I-85 onto I-385 I-385 North leads to downtown Greenville Go straight through two traffice lights and Hyatt Regency Greenville is on the left.