From Jackson head north 36 miles on Highway 49 North. When entering Yazoo City make a left at 15th street intersection. Then take a right on Grand Avenue and travel 1 mile to hotel. When coming in from the North on Highway 49 South enter Yazoo City and take a right at the Grand Avenue intersection. Hotel will be on your right. The Hampton Inn In Yazoo City occupies a modern town with an amazing range of shopping dining and convenience. The diverse culture of Yazoo County has produced a range of notable residents including the late comedian Jerry Clower. authors the late Willie Morris and Zig Zigler. actress Stella Stevens and blues singer Gatemouth Moore and Jack Owens. Whatever your interest - history the arts shopping recreation or commerce - you*ll find what you*re looking for where the Delta meets the hills in Yazoo County. So come stay with us at the Hampton Inn Yazoo City - Mississippi*s haven of shopping and convenience. Parking