From I-85 take Exit 40. Follow Hwy. 153 North to Hwy. 123 South. Hotel is on the left just behind Outback Steakhouse. This Property is 100 Pct. Non-Smoking The Hampton Inn Easley SC hotel is located just inside the city limits of Easley South Carolina. Our location is convenient to Easley Powdersville and Greenville SC. Whether traveling for business or pleasure our Hampton Inn hotel guests will enjoy a variety of amenities such as our complimentary On The House breakfast buffet served daily and complimentary high-speed internet access throughout the hotel. We love having you here in South Carolina at the Hampton Inn Easley hotel. Parking