Get directions to our hotel in Valley Park MO 63088. We are located conveniently right off I-44. Directly off of Interstate 44 exit number 272. We are at the intersection of 44 - Route 141. ***GPS USERS*** Please use the city VALLEY PARK when searching for our location. THIS PROPERTY IS 100 PCT NON SMOKING The Hampton Inn St. Louis Southwest MO hotel is located on the corner of Interstate 44 and Highway 141 at Exit 272 in southwest St. Louis Missouri. The hotel is near many corporations and attractions such as Six Flags the Fenton Daimler Chrysler Plant Maritz Inc. headquarters TQ3 Unigroup Corporation Anheuser Busch Soccer Park Grants Farm The Magic House Gravois Bluff shopping complex and the Fenton Missouri Manufacturing area. Our southwest St. Louis Hampton Inn offers pet friendly and amenity filled hotel rooms that include coffeemaker hair dryer refrigerator microwave iron and ironing board and complimentary high-speed internet access. Sure to please the busy executive or leisure Missouri traveler St. Louis Hampton Inn hotel guests will enjoy complimentary On the House hot breakfast buffet served daily. After a busy day hotel guests can relax in the outdoor pool or work out in the fitness center. We love having you here in Missouri at the Hampton Inn St. Louis Southwest hotel. Parking