From Route 15S - Exit at Motter Avenue. At light take a left onto Opossumtown Pike. Go to second light and turn left onto Thomas Johnson Drive. Make immediate left onto Taney Avenue. The hotel is on your left. From Route 15N - Exit at Motter Avenue. Bear right onto Opossumtown Pike. At third light turn left onto Thomas Johnson Drive. Make an immediate left onto Taney Avenue. The hotel is on your left. From I-270N - Follow to 15N. Exit Motter Avenue - bear right onto Opossumtown Pike. At third At the Hampton Inn - Suites Frederick-Fort Detrick hotel you*ll find exactly what you need. Whether you are traveling in Maryland for business or pleasure you*ll enjoy all the extras our hotel has to offer as well as a multitude of amenities in our spacious rooms and studio suites. Along with earning Hilton Honors points and miles our Frederick hotel guests will enjoy a complimentary On the House hot breakfast buffet daily and complimentary stays for children under 18 accompanied by a parent. Frederick Hampton Inn hotel amenities include an indoor pool and whirlpool fitness center business services four meeting rooms a guest laundry facility and a Suite Shop for snacks and essentials. Maryland travelers will also enjoy complimentary high-speed internet access in the guest rooms and throughout the hotel cable TV with complimentary movie channel and coffee and tea 24 hours a day in the lobby. We love having you here in Maryland at the Hampton Inn - Suites Frederick-Fort Detrick hotel. Parking light turn left onto Thomas Johnson Drive. Take an immediate left onto Taney Avenue. The hotel is on your left.