GPS Users Use 47 John Street Charleston SC 29403 From I-26 Columbia - Exit 221 also known as Meeting Street-Visitor Center. Right on Meeting Street. Turn right on John Street next to Visitor*s Center. Our hotel is on the left hand side. US 17 Southbound from Myrtle Beach - Cross Cooper River Bridge take Meeting Street Exit southbound. Turn right on John Street at the Visitors Center and our hotel is on the left. US 17 Northbound from Savannah - Bear right crossing Ashley River Bridge follow Effective February 27 2017 the Charleston Area Destination Fee has increased to USD 2.00 per night. The hotel is going 100pct non-smoking property. The Hampton Inn Charleston-Historic District hotel is located in the heart of downtown Charleston South Carolina. The hotel is adjacent to the Charleston Visitors Center and Charleston Museum. This award-winning hotel is the only antebellum hotel located in the Charleston Historic District. The hotel has utilized an 1860 restoration of a century-old railroad warehouse that features antebellum decor with pine floors mahogany furniture and oriental carpets. Relax outside in Historic Charleston*s largest garden courtyard or enjoy the meeting facilities seasonal packages downtown trolley service and concierge/bellman service. This South Carolina hotel*s amenities include complimentary hot breakfast in-room coffeemaker and TV with cable. The Hampton Inn Charleston also offers connecting rooms crib hair dryer iron and dry-cleaning service. Parking laundry/valet services and meeting/banquet facilities are available for a nominal fee. We love having you here at the Hampton Inn Charleston-Historic District hotel in South Carolina. Parking 17.00 USD signs to Visitor Center. Lockwood Dr. to Calhoun 8 lights left on Meeting St. Turn left on John Street. Entrance on the right. From Airport - Follow signs to 526 Columbia-Charleston. From 526 take I-26 East to Charleston. Exit 221 also known as Meeting Street. Turn right on Meeting Street then turn right on John Street at the Visitors Center. Our hotel is on the left.